The software architecture employed allows for rapid changes to be made to either the Graphical User Interface (GUI) or to the analytic modules. Moreover, Meta-Analyst includes a flexible tool to edit and customize generated meta-analysis graphs (e.g., forest plots) and provides output in many formats (images, Adobe PDF, Microsoft Word-ready RTF). The software performs several meta-analysis and meta-regression models for binary and continuous outcomes, as well as analyses for diagnostic and prognostic test studies in the frequentist and Bayesian frameworks. NET framework, and features a graphical user interface. Meta-Analyst is implemented in C# atop of the Microsoft. Herein, we introduce Meta-Analyst, a novel, powerful, intuitive, and free meta-analysis program for the meta-analysis of a variety of problems. In practice, most meta-analyses are performed in general statistical packages or dedicated meta-analysis programs. The theory and statistical foundations of meta-analysis continually evolve, providing solutions to many new and challenging problems. Meta-analysis is increasingly used as a key source of evidence synthesis to inform clinical practice.
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